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529-1011-00L 4 Credits BSC D-HEST , D-BIOL , D-CHAB
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Organic Chemistry I (for students of Biology, Pharmaceutical Sci., and Health Sci. & Tech.)

Organische Chemie I (für Biol./Pharm.Wiss./HST)

Lecturers & Examiners: Prof. Dr. Carlo Thilgen
VVZ CR n/a

Last Updated: 2026-02-05 15:36:24

Abstract

Fundamentals of Organic Chemistry: molecular structure. Bonding and functional groups; nomenclature; resonance and aromaticity; stereochemistry; conformation; bond strength; organic acids and bases; basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals.

Objective

Understanding the basic concepts and definitions of organic chemistry. Knowledge of the functional groups and classes of compounds that are important in biological systems. Foundations for the understanding of the relationship between structure and reactivity.

Content

Organic molecules: Isolation, separation and characterization of organic compounds. Classical structure theory: constitution, covalent bonding, bonding geometry, functional groups, classes of compounds, nomenclature. Electron delocalization: resonance, aromaticity. Stereochemistry: chirality, configuration, topicity. Conformational analysis. Bond energies, non-covalent interactions. Organic acids and bases. Basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals.

Resources

Lecture Notes

Printed lecture notes are available. Exercises, answer keys and other handouts can be downloaded from the Moodle course "Organic Chemistry I" of the current semester (https://moodle-app2.let.ethz.ch).

Literature

• Basisbuch Organische Chemie. Carsten Schmuck, Pearson Studium, 2018. (Kompaktes Lehrbuch für die ersten beiden Semester; 412 S.). • Organische Chemie. K. Peter C. Vollhardt, Neil E. Schore, Übers. hrsg. von Holger Butenschön, 5. Aufl., Wiley-VCH, 2011. • Organic Chemistry: Structure and Function. K. Peter C. Vollhardt, Neil E. Schore, 7th ed., W. H. Freeman & Company, 2014. • Organic Chemistry. T. W. Graham Solomons, Craig B. Fryhle, Scott A. Snyder, 11th ed., internat. stud. vers., Wiley, Hoboken, N. J., 2014. • Organische Chemie. J. Clayden, N. Greeves, S. Warren, 2. Aufl., Springer Spektrum, 2013. • Organic Chemistry. J. Clayden, N. Greeves, S. Warren, 2nd ed., Oxford University Press, 2012. • Organische Chemie. Paula Y. Bruice, 5. akt. Aufl., Pearson. • Organic Chemistry (Global Edition). Paula Y. Bruice, 8th ed., Pearson. • Essential Organic Chemistry (Global Edition). Paula Y. Bruice, 3rd ed., Pearson. (Designed for a one-term course) • Organic Chemistry I as a Second Language – Translating the basic concepts (Taschenbuch mit Übungen: 656 Seiten). David R. Klein; Verlag: John Wiley & Sons Inc; ISBN-10: 0470198699, ISBN-13: 978-0470198698.

General Information

Language
German
Levels
BSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 75 minutes
Aids
Leere Papierblätter und Schreibstifte dürfen mitgebracht werden.
Digital
The exam takes place on devices provided by ETH Zurich.
Online-Prüfung.

Course Components

Type Title Time & Place Hours
lecture with exercise Organische Chemie I (für Biol./Pharm.Wiss./HST)
Groups are selected in myStudies. Die Vorlesungen findet am MIttwoch von 10-12 ONLINE statt zu folgenden Zeiten: Mittwochs, von 9:45:00 bis 11:30 Uhr Zusätzlich Freitag 18. September Freitag 25. September Freitag 20. November Freitag 18. Dezember jeweils von 13:45:00 bis 15:30:00 Die Übungen beginnen erst in der dritten Semesterwoche und sind wie folgt vorgesehen: Fr 14-16 oder 16-18 Uhr (nach Einteilung) in Präsenz.
  • Wed 09:45-11:30 (HCI G 7)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 14:00-16:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • Fri 16:00-18:00 (ON LI NE)
  • 18.09 Date 13:45-15:30 (HPH G 1)
  • 25.09 Date 13:45-15:30 (HPH G 1)
  • 20.11 Date 13:45-15:30 (HPH G 1)
  • 18.12 Date 13:45-15:30 (HCI G 3)
  • 18.12 Date 15:45-16:30 (HCI G 3)
4 h weekly

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