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551-1129-00L 6 Credits BSC D-BIOL
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Understanding and Engineering Microbial Metabolism

Lecturers & Examiners: Prof. Dr. Julia Vorholt-Zambelli
Number of participants limited to 6. The enrolment is done by the D-BIOL study administration. General safety regulations for all block courses: -Whenever possible the distance rules have to be respected -All students have to wear masks throughout the course (keep reserve masks ready) -The installation and activation of the Swiss Covid-App is highly encouraged -Any additional rules for individual courses have to be respected -Students showing any COVID-19 symptoms are not allowed to enter ETH buildings and have to inform the course responsible
VVZ CR n/a

Last Updated: 2026-02-05 15:36:22

Abstract

This laboratory course has a focus on current research topics in our laboratory related to metabolic engineering, the general understanding of metabolism, and is partially focused on one carbon metabolism. Projects will be conducted in small groups.

Objective

The course aims at introducing technologies to investigate bacterial metabolism and key principles of metabolic engineering. The main focus of this block course is on practical work and will familiarize participants with complementary approaches, in particular genetic, biochemical and analytical techniques including metabolomics. Results will be presented by students in scientific presentations. Another goal is to learn how to write a scientific report.

Content

The course and will include topics such as pathway elucidation & engineering and related ongoing research projects in the lab. Experimental work applied during the course will comprise methods such as cloning work & transformation, growth determination, enzyme activity assays, liquid-chromatography mass-spectrometry and dynamic labeling experiments.

Resources

Lecture Notes

None

Literature

Will be provided at the beginning of the course.

General Information

Language
English
Levels
BSC
Frequency
Yearly recurring

Examination

Type
graded semester performance
Student evaluations will be based on an exam, a project presentation and a written report.Details will be communicated at the beginning of the course.

Course Components

Type Title Time & Place Hours
practical/laboratory course Understanding and Engineering Microbial Metabolism
Permission from lecturers required for all students. Block course in the 3rdt quarter of the autumn semester Place: HCI F436
No time listed 100 h semesterly

Offered In