This course will consider the pathogenetic landscape of cancer and its progression to metastasis, explore how abnormalities of cellular information management cause cancer and demonstrate how the integrated application of modern profiling technologies, mouse cancer models and human pathology provides a foundation for developing individualized cancer therapeutics.

This Course introduces principle concepts, techniques, and experimental strategies used in modern Cell Biology. Major topics include: neuron-glia interactions in health and disease; mitochondrial dynamics; stem cell biology; growth factor action in development, tissue repair and disease; cancer biology; cell metabolism.

This introductory Laboratory course introduces the student to the entire range of classical and modern molecular biosciences. In the second year (Praktikum GL Bio II) the students will perform three praktikum days in:- Plant Biology- Animal Models- Genomics- Molecular Systems Biology(total of 12 experiments)Each experiment takes one full day.

The lecture conveys the fundamental concepts underlying multicellularity with an emphasis on the molecular basis of multicellular biological systems and their functional integration into coherent wholes. The structural and functional specialization in multicellular organisms will be discussed by highlighting common and specific functions in fungi, plants, and animals (including humans).

The course builds on the Fundamentals in Biology courses that are taught during the first three semesters. Students will be introduced into molecular disease mechanisms with a focus on the immune system and its role in health and disease and on cancer biology.