The lecture guides through the entire implant development process from concept to market. It illustrates how mitigation of risks during the development of patient-centered implants catalyzes innovations while simultaneously meeting user needs, socio-economic requirements, and economic targets. Discussions include real-world case studies and trends in orthopedics and cardiovascular surgery.

The seminar provides state-of-the-art insight to the biomechanical function of bone from molecules, to cells, tissue and up to the organ. Multiscale imaging and simulation allows linking different levels of hierarchy, where systems biology helps understanding the mechanobiological response of bone to loading and injury in scenarios relevant for personalized health and translational medicine.