Knowledge about the fundamentals of pharmacokinetics and pharmacokinetic modelling, the basic concepts of pharmacology and toxicology, radiopharmaceutical monographs in the European pharmacopoeia, radiological imaging modalities and the basics of applied statistics in biomedical research. Understanding the fundamentals of nuclear medicine: Diagnostic applications in neurology and oncology therapy.

The course comprises experiments relating to concepts of medicinal chemistry including statistical processing, fitting of experimental data, computer modeling of protein structures, experimental measurement of affinity constants and kinetic dissociation constants for protein ligands. The chemical stability of a drug will be studied. Basic gene cloning and protein expression will be introduced.

-Molecular imaging in drug development-Radiopharmaceutical syntheses-Knowledge of the physical principles of radioactivity-Structure and function of radiopharmaceuticals-Examples of application in diagnosis and therapy in humans-Targeted radionuclide therapy

State-of-the-art information on drug discovery and development by experts from academia and industry.